6GMU

Serum paraoxonase-1 by directed evolution with the L69G/H134R/F222S/T332S mutations

Summary for 6GMU

DescriptorSerum Paraoxonase-1 by directed evolution with the L69G/H134R/F222S/T332S mutations, CALCIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsbeta-propeller, lactonase, hdl, organophosphate-hydrolase, hydrolase
Biological sourceHomo sapiens
Total number of polymer chains1
Total molecular weight39961.62
Authors
Ben-David, M.,Sussman, J.L.,Tawfik, D.S. (deposition date: 2018-05-28, release date: 2019-04-17)
Primary citation
Ben-David, M.,Joel, L.S.,Dan, S.T.
An epistatic ratchet versus a reversible transition in the evolution of enzyme function
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22930 1.8% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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