6GJZ
CryoEM structure of the MDA5-dsRNA filament in complex with AMPPNP
Summary for 6GJZ
Entry DOI | 10.2210/pdb6gjz/pdb |
Related | 6G19 6G1S 6G1X |
EMDB information | 0012 4338 4340 4341 |
Descriptor | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ... (5 entities in total) |
Functional Keywords | protein-rna complex, helical filament, atpase, innate immune receptor, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 123726.51 |
Authors | |
Primary citation | Yu, Q.,Qu, K.,Modis, Y. Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72:999-1012.e6, 2018 Cited by PubMed: 30449722DOI: 10.1016/j.molcel.2018.10.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.06 Å) |
Structure validation
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