6GJO
Crystal Structure of Glycogen Synthase Kinase-3 beta in Complex with BI-91BS
Summary for 6GJO
Entry DOI | 10.2210/pdb6gjo/pdb |
Descriptor | Glycogen synthase kinase-3 beta, (3~{Z})-5-ethanoyl-3-[[(1-methylpiperidin-4-yl)amino]-phenyl-methylidene]-1~{H}-indol-2-one (3 entities in total) |
Functional Keywords | kinase, indolinone, gsk3, atp-binding, nucleotide-binding, serine/threonine-protein kinase, wnt signaling pathway, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 92979.71 |
Authors | Hoerer, S. (deposition date: 2018-05-16, release date: 2019-03-27, Last modification date: 2024-05-15) |
Primary citation | Hoerer, S. CRYSTAL STRUCTURE OF Glycogen synthase kinase-3 beta IN COMPLEX WITH BI-91BS To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
Download full validation report