6GJH
Human Hsp27 (HspB1) alpha-crystallin domain in complex with a peptide mimic of its phosphorylatable N-terminal region
Summary for 6GJH
Entry DOI | 10.2210/pdb6gjh/pdb |
Descriptor | Heat shock protein beta-1, ALA-LEU-SER-ARG-GLN, LEU-SER-GLY-VAL, ... (6 entities in total) |
Functional Keywords | ig-fold, shsp, chaperone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 79676.54 |
Authors | Collier, M.P.,Benesch, J.L.P. (deposition date: 2018-05-16, release date: 2019-05-29, Last modification date: 2024-10-16) |
Primary citation | Collier, M.P.,Alderson, T.R.,de Villiers, C.P.,Nicholls, D.,Gastall, H.Y.,Allison, T.M.,Degiacomi, M.T.,Jiang, H.,Mlynek, G.,Furst, D.O.,van der Ven, P.F.M.,Djinovic-Carugo, K.,Baldwin, A.J.,Watkins, H.,Gehmlich, K.,Benesch, J.L.P. HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C. Sci Adv, 5:eaav8421-eaav8421, 2019 Cited by PubMed: 31131323DOI: 10.1126/sciadv.aav8421 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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