6GJ4
Tubulin-6j complex
Summary for 6GJ4
Entry DOI | 10.2210/pdb6gj4/pdb |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 6 |
Total formula weight | 265303.10 |
Authors | Brindisi, M.,Ulivieri, C.,Alfano, G.,Gemma, S.,Balaguer, F.d.A.,Khan, T.,Grillo, A.,Chemi, G.,Menchon, G.,Prota, A.E.,Olieric, N.,Agell, D.L.,Barasoain, I.,Diaz, J.F.,Nebbioso, A.,Conte, M.R.,Lopresti, L.,Magnano, S.,Amet, R.,Kinsella, P.,Zisterer, D.M.,Ibrahim, O.,O'Sullivan, J.,Morbidelli, L.,Spaccapelo, R.,Baldari, C.,Butini, S.,Novellino, E.,Campiani, G.,Altucci, L.,Steinmetz, M.O.,Brogi, S. (deposition date: 2018-05-16, release date: 2018-12-05, Last modification date: 2024-01-17) |
Primary citation | Brindisi, M.,Ulivieri, C.,Alfano, G.,Gemma, S.,de Asis Balaguer, F.,Khan, T.,Grillo, A.,Chemi, G.,Menchon, G.,Prota, A.E.,Olieric, N.,Lucena-Agell, D.,Barasoain, I.,Diaz, J.F.,Nebbioso, A.,Conte, M.,Lopresti, L.,Magnano, S.,Amet, R.,Kinsella, P.,Zisterer, D.M.,Ibrahim, O.,O'Sullivan, J.,Morbidelli, L.,Spaccapelo, R.,Baldari, C.,Butini, S.,Novellino, E.,Campiani, G.,Altucci, L.,Steinmetz, M.O.,Brogi, S. Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents. Eur J Med Chem, 162:290-320, 2018 Cited by PubMed: 30448418DOI: 10.1016/j.ejmech.2018.11.004 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)