6GHX

Alzheimer's Amyloid-Beta Peptide Fragment 31-35 in Complex with Cd-substituted Thermolysin

Summary for 6GHX

Entry DOI	10.2210/pdb6ghx/pdb
Related	5ONP 5ONQ 5ONR
Descriptor	Thermolysin, CALCIUM ION, CADMIUM ION, ... (6 entities in total)
Functional Keywords	peptidase, protein-peptide complex, hydrolase
Biological source	Geobacillus stearothermophilus
Total number of polymer chains	1
Total formula weight	34973.54
Authors	Leite, J.P.,Gales, L. (deposition date: 2018-05-09, release date: 2019-02-06, Last modification date: 2024-01-17)
Primary citation	Leite, J.P.,Gales, L. Alzheimer's A beta1-40peptide degradation by thermolysin: evidence of inhibition by a C-terminal A beta product. FEBS Lett., 593:128-137, 2019 Cited by PubMed: 30403288 DOI: 10.1002/1873-3468.13285 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.156 Å)

Structure validation