6GHM

Structure of PP1 alpha phosphatase bound to ASPP2

Summary for 6GHM

Entry DOI	10.2210/pdb6ghm/pdb
Descriptor	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Apoptosis-stimulating of p53 protein 2, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywords	phosphatase, pp1, aspp2, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	125588.85
Authors	Mouilleron, S.,Bertran, T.M.,Tapon, N.,Zhou, Y. (deposition date: 2018-05-08, release date: 2019-02-27, Last modification date: 2024-01-17)
Primary citation	Bertran, M.T.,Mouilleron, S.,Zhou, Y.,Bajaj, R.,Uliana, F.,Kumar, G.S.,van Drogen, A.,Lee, R.,Banerjee, J.J.,Hauri, S.,O'Reilly, N.,Gstaiger, M.,Page, R.,Peti, W.,Tapon, N. ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail. Nat Commun, 10:771-771, 2019 Cited by PubMed: 30770806 DOI: 10.1038/s41467-019-08686-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation