6GGG
Mineralocorticoid receptor in complex with (s)-13
Summary for 6GGG
Entry DOI | 10.2210/pdb6ggg/pdb |
Related | 6GEV 6GG8 |
Descriptor | Mineralocorticoid receptor, NCOA1 peptide, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | mineralocorticoid receptor, nuclear hormone receptor, steroid receptor, ligand complex, peptide complex, signaling protein, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 37049.64 |
Authors | Edman, K.,Aagaard, A.,Tangefjord, S. (deposition date: 2018-05-03, release date: 2019-01-09, Last modification date: 2024-01-17) |
Primary citation | Granberg, K.L.,Yuan, Z.Q.,Lindmark, B.,Edman, K.,Kajanus, J.,Hogner, A.,Malmgren, M.,O'Mahony, G.,Nordqvist, A.,Lindberg, J.,Tangefjord, S.,Kossenjans, M.,Lofberg, C.,Branalt, J.,Liu, D.,Selmi, N.,Nikitidis, G.,Nordberg, P.,Hayen, A.,Aagaard, A.,Hansson, E.,Hermansson, M.,Ivarsson, I.,Jansson-Lofmark, R.,Karlsson, U.,Johansson, U.,William-Olsson, L.,Hartleib-Geschwindner, J.,Bamberg, K. Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection. J.Med.Chem., 62:1385-1406, 2019 Cited by PubMed: 30596500DOI: 10.1021/acs.jmedchem.8b01523 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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