Molecular basis of egg coat filament cross-linking: high-resolution structure of the partially deglycosylated ZP1 ZP-N1 domain homodimer

Summary for 6GF6

Related6GF7 6GF8
DescriptorZona pellucida sperm-binding protein 1,Zona pellucida sperm-binding protein 1, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ... (4 entities in total)
Functional Keywordszona pellucida, zp1, zp-n domain, zp module, zp domain, egg coat filament cross-linking, egg coat penetration by sperm, cell adhesion
Biological sourceGallus gallus (Chicken)
Total number of polymer chains2
Total molecular weight31505.48
Nishimura, K.,Jovine, L. (deposition date: 2018-04-29, release date: 2019-06-19, Last modification date: 2019-07-24)
Primary citation
Nishimura, K.,Dioguardi, E.,Nishio, S.,Villa, A.,Han, L.,Matsuda, T.,Jovine, L.
Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility.
Nat Commun, 10:3086-3086, 2019
PubMed: 31300655 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-10931-5
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23010 1.1% 9.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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