6GF2

The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome

6GF2 の概要

• エントリーDOI: 10.2210/pdb6gf2/pdb
• NMR情報: BMRB: 27466
• 分子名称: Ubiquitin D (1 entity in total)
• 機能のキーワード: fat10, ubiquitin-like modifier, proteasome, degradation, immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9263.70

構造登録者

Aichem, A.,Anders, S.,Catone, N.,Roessler, P.,Stotz, S.,Berg, A.,Schwab, R.,Scheuermann, S.,Bialas, J.,Schmidtke, G.,Peter, C.,Groettrup, M.,Wiesner, S. (登録日: 2018-04-29, 公開日: 2018-08-08, 最終更新日: 2024-06-19)

• 主引用文献: Aichem, A.,Anders, S.,Catone, N.,Stotz, S.,Berg, A.,Schwab, R.,Scheuermann, S.,Bialas, J.,Schutz-Stoffregen, M.C.,Schmidtke, G.,Peter, C.,Groettrup, M.,Wiesner, S.; The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.; Nat Commun, 9:3321-3321, 2018; PubMed: 30127417; DOI: 10.1038/s41467-018-05776-3

実験手法

SOLUTION NMR