6GBL

Repertoires of functionally diverse enzymes through computational design at epistatic active-site positions

Summary for 6GBL

Entry DOI	10.2210/pdb6gbl/pdb
Related	6GBJ 6GBK
Descriptor	Parathion hydrolase, FORMIC ACID, ZINC ION, ... (6 entities in total)
Functional Keywords	phosphotriesterase, hydrolase
Biological source	Brevundimonas diminuta (Pseudomonas diminuta)
Total number of polymer chains	2
Total formula weight	74018.43
Authors	Khersonsky, O.,Lipsh, R.,Avizemer, Z.,Goldsmith, M.,Ashani, Y.,Leader, H.,Dym, O.,Rogotner, S.,Trudeau, D.,Tawfik, D.S.,Fleishman, S.J. (deposition date: 2018-04-15, release date: 2018-10-24, Last modification date: 2024-01-17)
Primary citation	Khersonsky, O.,Lipsh, R.,Avizemer, Z.,Ashani, Y.,Goldsmith, M.,Leader, H.,Dym, O.,Rogotner, S.,Trudeau, D.L.,Prilusky, J.,Amengual-Rigo, P.,Guallar, V.,Tawfik, D.S.,Fleishman, S.J. Automated Design of Efficient and Functionally Diverse Enzyme Repertoires. Mol. Cell, 72:178-186.e5, 2018 Cited by PubMed: 30270109 DOI: 10.1016/j.molcel.2018.08.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation