6G9V
Crystal structure of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase(AfUAP1) in complex with UDPGlcNAc, pyrophosphate and Mg2+
Summary for 6G9V
Entry DOI | 10.2210/pdb6g9v/pdb |
Descriptor | UDP-N-acetylglucosamine pyrophosphorylase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, PYROPHOSPHATE, ... (5 entities in total) |
Functional Keywords | cell wall, anti fungal, pyrophosphorylase, aspergillus fumigatus, transferase |
Biological source | Aspergillus fumigatus Af293 |
Total number of polymer chains | 2 |
Total formula weight | 114396.81 |
Authors | Raimi, O.G.,Hurtado-Guerrero, R.,Borodin, V.,Urbaniak, M.,Ferguson, M.,van Aalten, D. (deposition date: 2018-04-11, release date: 2019-04-24, Last modification date: 2024-01-17) |
Primary citation | Raimi, O.G.,Hurtado-Guerrero, R.,Borodkin, V.,Ferenbach, A.,Urbaniak, M.D.,Ferguson, M.A.J.,van Aalten, D.M.F. A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor RSC Chem. Biol., 2020 Cited by DOI: 10.1039/C9CB00017HPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report