6G82
Serum paraoxonase-1 by directed evolution with the L69S/H115W/F222S mutations
Summary for 6G82
Entry DOI | 10.2210/pdb6g82/pdb |
Descriptor | Serum paraoxonase-1 by directed evolution with the L69S/H115W/F222S mutations, CALCIUM ION (3 entities in total) |
Functional Keywords | beta-propeller, lactonase, hdl, organophosphate-hydrolase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 39646.00 |
Authors | Ben-David, M.,Sussman, J.L.,Tawfik, D.S. (deposition date: 2018-04-07, release date: 2019-03-20, Last modification date: 2024-01-17) |
Primary citation | Ben-David, M.,Soskine, M.,Dubovetskyi, A.,Cherukuri, K.P.,Dym, O.,Sussman, J.L.,Liao, Q.,Szeler, K.,Kamerlin, S.C.L.,Tawfik, D.S. Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition. Mol.Biol.Evol., 37:1133-1147, 2020 Cited by PubMed: 31873734DOI: 10.1093/molbev/msz298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.401 Å) |
Structure validation
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