6G6X

14-3-3sigma in complex with a P129beta3P mutated YAP pS127 phosphopeptide

Summary for 6G6X

Entry DOI	10.2210/pdb6g6x/pdb
Descriptor	14-3-3 protein sigma, Transcriptional coactivator YAP1, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	beta amino acid hippo pathway yap/taz, oncoprotein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	27905.90
Authors	Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-03, release date: 2019-04-10, Last modification date: 2024-01-17)
Primary citation	Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins. Chem.Commun.(Camb.), 55:14809-14812, 2019 Cited by PubMed: 31763628 DOI: 10.1039/c9cc07982c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.13 Å)

Structure validation