6G4L
17beta-hydroxysteroid Dehydrogenase Type 14 Mutant Y253A in Complex With a Non-steroidal Inhibitor
Summary for 6G4L
| Entry DOI | 10.2210/pdb6g4l/pdb |
| Descriptor | 17-beta-hydroxysteroid dehydrogenase 14, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... (7 entities in total) |
| Functional Keywords | inhibitor complex mutant, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29585.43 |
| Authors | Badran, M.,Klebe, G.,Heine, A.,Marchais-Oberwinkler, S. (deposition date: 2018-03-27, release date: 2019-04-10, Last modification date: 2024-01-17) |
| Primary citation | Badran, M.,Bertoletti, N.,Keils, A.,Heine, A.,Klebe, G.,Marchais-Oberwinkler, S. Mutational and structural studies uncover crucial amino acids determining activity and stability of 17beta-HSD14 J.Steroid Biochem.Mol.Biol., 2019 Cited by DOI: 10.1016/j.jsbmb.2019.02.009PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.444 Å) |
Structure validation
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