6G46

Red kidney bean purple acid phosphatase in complex with 2-(Naphthalen-1-yl)thiazole-4-carboxylic acid

6G46 の概要

• エントリーDOI: 10.2210/pdb6g46/pdb
• 分子名称: Fe(3+)-Zn(2+) purple acid phosphatase, SODIUM ION, ISOPROPYL ALCOHOL, ... (13 entities in total)
• 機能のキーワード: phosphatase, metallohydrolase, hydrolase, metalloprotein, purple acid phosphatase, pap, red kidney bean, rkbpap, drug design, drug discovery, rational drug design, osteoporosis, metal binding protein
• 由来する生物種: Phaseolus vulgaris (Kidney bean)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 206715.09

構造登録者

Feder, D.F. (登録日: 2018-03-26, 公開日: 2018-09-26, 最終更新日: 2024-01-17)

• 主引用文献: Hussein, W.M.,Feder, D.,Schenk, G.,Guddat, L.W.,McGeary, R.P.; Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics.; Eur J Med Chem, 157:462-479, 2018; PubMed: 30107365; DOI: 10.1016/j.ejmech.2018.08.004

実験手法

X-RAY DIFFRACTION (2.4 Å)