6G2V
Crystal structure of the p97 D2 domain in a helical split-washer conformation
Summary for 6G2V
Entry DOI | 10.2210/pdb6g2v/pdb |
Descriptor | Transitional endoplasmic reticulum ATPase, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | atpase, p97, protein degradation, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31939.62 |
Authors | Stach, L.,Morgan, R.M.L.,Freemont, P.S. (deposition date: 2018-03-23, release date: 2019-04-10, Last modification date: 2024-01-17) |
Primary citation | Stach, L.,Morgan, R.M.,Makhlouf, L.,Douangamath, A.,von Delft, F.,Zhang, X.,Freemont, P.S. Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding. Febs Lett., 594:933-943, 2020 Cited by PubMed: 31701538DOI: 10.1002/1873-3468.13667 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.903 Å) |
Structure validation
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