6G1L

MITF/CLEARbox structure

Summary for 6G1L

• Entry DOI: 10.2210/pdb6g1l/pdb
• Descriptor: Microphthalmia-associated transcription factor, CLEAR-box (3 entities in total)
• Functional Keywords: melanocyte, autophagy, transcription factor, dna binding, transcription
• Biological source: Mus musculus (House Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 19249.76

Authors

Pogenberg, V.,Wilmanns, M. (deposition date: 2018-03-21, release date: 2019-02-06, Last modification date: 2024-01-17)

• Primary citation: Moller, K.,Sigurbjornsdottir, S.,Arnthorsson, A.O.,Pogenberg, V.,Dilshat, R.,Fock, V.,Brynjolfsdottir, S.H.,Bindesboll, C.,Bessadottir, M.,Ogmundsdottir, H.M.,Simonsen, A.,Larue, L.,Wilmanns, M.,Thorsson, V.,Steingrimsson, E.,Ogmundsdottir, M.H.; MITF has a central role in regulating starvation-induced autophagy in melanoma.; Sci Rep, 9:1055-1055, 2019; PubMed: 30705290; DOI: 10.1038/s41598-018-37522-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)