6G0F

BRD4 (BD1) in complex with docking-derived ligand

Summary for 6G0F

• Entry DOI: 10.2210/pdb6g0f/pdb
• Descriptor: Bromodomain-containing protein 4, 1,2-ETHANEDIOL, (4~{R})-4-(5-bromanyl-2-fluoranyl-phenyl)-5,6,7-trimethoxy-3,4-dihydro-1~{H}-quinolin-2-one, ... (4 entities in total)
• Functional Keywords: brd4, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15571.68

Authors

Pretzel, J.,Humbeck, L. (deposition date: 2018-03-18, release date: 2020-01-08, Last modification date: 2024-01-17)

• Primary citation: Humbeck, L.,Pretzel, J.,Spitzer, S.,Koch, O.; Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARgamma; Chemrxiv, 2019; DOI: 10.26434/chemrxiv.11472618

Experimental method

X-RAY DIFFRACTION (1.618 Å)