6G02

Complex of neuraminidase from H1N1 influenza virus with tamiphosphor omega-azidohexyl ester

6G02 の概要

• エントリーDOI: 10.2210/pdb6g02/pdb
• 関連するPDBエントリー: 6G01
• 分子名称: Neuraminidase, CALCIUM ION, 6-[[(3~{R},4~{R},5~{S})-4-acetamido-5-azanyl-3-pentan-3-yloxy-cyclohexen-1-yl]-oxidanyl-phosphoryl]oxyhexylimino-azanylidene-azanium, ... (6 entities in total)
• 機能のキーワード: neuraminidase, influenza, complex, inhibitor, viral protein
• 由来する生物種: Influenza A virus (A/California/07/2009(H1N1))
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88220.13

構造登録者

Pachl, P.,Pokorna, J. (登録日: 2018-03-15, 公開日: 2019-01-23, 最終更新日: 2020-07-29)

• 主引用文献: Kozisek, M.,Navratil, V.,Rojikova, K.,Pokorna, J.,Berenguer Albinana, C.,Pachl, P.,Zemanova, J.,Machara, A.,Sacha, P.,Hudlicky, J.,Cisarova, I.,Rezacova, P.,Konvalinka, J.; DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.; Biochem. J., 475:3847-3860, 2018; PubMed: 30404922; DOI: 10.1042/BCJ20180764

実験手法

X-RAY DIFFRACTION (1.84 Å)