Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Gal, Hg2+ Soak

Summary for 6FXX

DescriptorProcollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, MERCURY (II) ION, ... (8 entities in total)
Functional Keywordslysyl hydroxylase, galacosyltransferase, glucosyltransferase, collagen, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight84858.78
Primary citation
Scietti, L.,Chiapparino, A.,De Giorgi, F.,Fumagalli, M.,Khoriauli, L.,Nergadze, S.,Basu, S.,Olieric, V.,Cucca, L.,Banushi, B.,Profumo, A.,Giulotto, E.,Gissen, P.,Forneris, F.
Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9:3163-3163, 2018
PubMed: 30089812 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-05631-5
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25940.3%1.1%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution