6FWO

Structure of an E336Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-1,2-anhydro-mannose hydrolyzed by enzyme

Summary for 6FWO

Entry DOI	10.2210/pdb6fwo/pdb
Related	6FWG 6FWI 6FWJ 6FWL 6FWM 6FWP 6FWQ
Descriptor	Glycosyl hydrolase family 71, ACETATE ION, (1~{S},2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Bacteroides xylanisolvens XB1A
Total number of polymer chains	1
Total formula weight	44409.04
Authors	Sobala, L.F.,Speciale, G.,Hakki, Z.,Fernandes, P.Z.,Raich, L.,Rojas-Cervellera, V.,Bennet, A.,Thompson, A.J.,Bernardo-Seisdedos, G.,Millet, O.,Zhu, S.,Lu, D.,Sollogoub, M.,Rovira, C.,Jimenez-Barbero, J.,Davies, G.J.,Williams, S.J. (deposition date: 2018-03-06, release date: 2019-09-18, Last modification date: 2024-01-17)
Primary citation	Sobala, L.F.,Speciale, G.,Zhu, S.,Raich, L.,Sannikova, N.,Thompson, A.J.,Hakki, Z.,Lu, D.,Shamsi Kazem Abadi, S.,Lewis, A.R.,Rojas-Cervellera, V.,Bernardo-Seisdedos, G.,Zhang, Y.,Millet, O.,Jimenez-Barbero, J.,Bennet, A.J.,Sollogoub, M.,Rovira, C.,Davies, G.J.,Williams, S.J. An Epoxide Intermediate in Glycosidase Catalysis. Acs Cent.Sci., 6:760-770, 2020 Cited by PubMed: 32490192 DOI: 10.1021/acscentsci.0c00111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.34 Å)

Structure validation