6FVS

The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Barium ions (Ba2+)

6FVS の概要

• エントリーDOI: 10.2210/pdb6fvs/pdb
• 分子名称: Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside, BARIUM ION, ... (5 entities in total)
• 機能のキーワード: pentameric ligand-gated ion channel., membrane protein
• 由来する生物種: endosymbiont of Tevnia jerichonana (vent Tica)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 188426.14

構造登録者

Hu, H.,Delarue, M. (登録日: 2018-03-05, 公開日: 2018-05-16, 最終更新日: 2024-05-08)

• 主引用文献: Hu, H.,Nemecz, A.,Van Renterghem, C.,Fourati, Z.,Sauguet, L.,Corringer, P.J.,Delarue, M.; Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.; Proc. Natl. Acad. Sci. U.S.A., 115:E3959-E3968, 2018; PubMed: 29632192; DOI: 10.1073/pnas.1717700115

実験手法

X-RAY DIFFRACTION (3.2 Å)