6FUY

Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)

Replaces:  6FMM

Summary for 6FUY

• Entry DOI: 10.2210/pdb6fuy/pdb
• Descriptor: Vinculin, CALCIUM ION (3 entities in total)
• Functional Keywords: mechanosensitive self-inhibition adapter, cell adhesion
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P18206
• Total number of polymer chains: 1
• Total formula weight: 116699.31

Authors

Chorev, D.S.,Volberg, T.,Livne, A.,Eisenstein, M.,Martins, B.,Kam, Z.,Jockusch, B.M.,Medalia, O.,Sharon, M.,Geiger, B. (deposition date: 2018-02-28, release date: 2018-03-14, Last modification date: 2024-01-17)

• Primary citation: Chorev, D.S.,Volberg, T.,Livne, A.,Eisenstein, M.,Martins, B.,Kam, Z.,Jockusch, B.M.,Medalia, O.,Sharon, M.,Geiger, B.; Conformational states during vinculin unlocking differentially regulate focal adhesion properties.; Sci Rep, 8:2693-2693, 2018; PubMed: 29426917; DOI: 10.1038/s41598-018-21006-8

Experimental method

X-RAY DIFFRACTION (3 Å)