6FUX

Structure of aminoglycoside phosphotransferase APH(3'')-Id from Streptomyces rimosus ATCC10970 in complex with ADP and streptomycin

Summary for 6FUX

• Entry DOI: 10.2210/pdb6fux/pdb
• Related: 6FUC
• Descriptor: Aminoglycoside phosphotransferase, GLYCEROL, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: streptomyces rimosus, aminoglycoside phosphotransferase, antibiotic resistance, streptomycin, phosphorylation, atp binding, kinase activity, transferase
• Biological source: Streptomyces rimosus subsp. rimosus ATCC 10970
• Total number of polymer chains: 1
• Total formula weight: 30944.30

Authors

Boyko, K.M.,Nikolaeva, A.Y.,Korzhenevskiy, D.A.,Alekseeva, M.G.,Mavletova, D.A.,Zakharevich, N.V.,Rudakova, N.N.,Danilenko, V.N.,Popov, V.O. (deposition date: 2018-02-28, release date: 2019-03-20, Last modification date: 2024-01-17)

• Primary citation: Alekseeva, M.G.,Boyko, K.M.,Nikolaeva, A.Y.,Mavletova, D.A.,Rudakova, N.N.,Zakharevich, N.V.,Korzhenevskiy, D.A.,Ziganshin, R.H.,Popov, V.O.,Danilenko, V.N.; Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH(3′′)-Id from Streptomyces rimosus subsp. rimosus ATCC 10970.; Arch.Biochem.Biophys., 671:111-122, 2019; PubMed: 31251922; DOI: 10.1016/j.abb.2019.06.008

Experimental method

X-RAY DIFFRACTION (1.65 Å)