6FUX

Structure of aminoglycoside phosphotransferase APH(3'')-Id from Streptomyces rimosus ATCC10970 in complex with ADP and streptomycin

6FUX の概要

• エントリーDOI: 10.2210/pdb6fux/pdb
• 関連するPDBエントリー: 6FUC
• 分子名称: Aminoglycoside phosphotransferase, GLYCEROL, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: streptomyces rimosus, aminoglycoside phosphotransferase, antibiotic resistance, streptomycin, phosphorylation, atp binding, kinase activity, transferase
• 由来する生物種: Streptomyces rimosus subsp. rimosus ATCC 10970
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30944.30

構造登録者

Boyko, K.M.,Nikolaeva, A.Y.,Korzhenevskiy, D.A.,Alekseeva, M.G.,Mavletova, D.A.,Zakharevich, N.V.,Rudakova, N.N.,Danilenko, V.N.,Popov, V.O. (登録日: 2018-02-28, 公開日: 2019-03-20, 最終更新日: 2024-01-17)

• 主引用文献: Alekseeva, M.G.,Boyko, K.M.,Nikolaeva, A.Y.,Mavletova, D.A.,Rudakova, N.N.,Zakharevich, N.V.,Korzhenevskiy, D.A.,Ziganshin, R.H.,Popov, V.O.,Danilenko, V.N.; Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH(3′′)-Id from Streptomyces rimosus subsp. rimosus ATCC 10970.; Arch.Biochem.Biophys., 671:111-122, 2019; PubMed: 31251922; DOI: 10.1016/j.abb.2019.06.008

実験手法

X-RAY DIFFRACTION (1.65 Å)