6FTZ
COMPLEMENT FACTOR D COMPLEXED WITH COMPOUND 6
Summary for 6FTZ
| Entry DOI | 10.2210/pdb6ftz/pdb |
| Descriptor | Complement factor D, ~{N}4-[3-(aminomethyl)phenyl]-1~{H}-indole-2,4-dicarboxamide (3 entities in total) |
| Functional Keywords | serine protease, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 25047.46 |
| Authors | Ostermann, N. (deposition date: 2018-02-26, release date: 2018-06-06, Last modification date: 2024-01-17) |
| Primary citation | Vulpetti, A.,Ostermann, N.,Randl, S.,Yoon, T.,Mac Sweeney, A.,Cumin, F.,Lorthiois, E.,Rudisser, S.,Erbel, P.,Maibaum, J. Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D. ACS Med Chem Lett, 9:490-495, 2018 Cited by PubMed: 29795765DOI: 10.1021/acsmedchemlett.8b00104 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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