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6FTY

COMPLEMENT FACTOR D COMPLEXED WITH COMPOUND 5

Summary for 6FTY
Entry DOI10.2210/pdb6fty/pdb
DescriptorComplement factor D, 4-[[(5~{S},7~{R})-3-azanyl-1-adamantyl]carbonylamino]-1~{H}-indole-2-carboxamide, GLYCEROL, ... (4 entities in total)
Functional Keywordsserine protease, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight25183.65
Authors
Ostermann, N. (deposition date: 2018-02-26, release date: 2018-06-06, Last modification date: 2024-01-17)
Primary citationVulpetti, A.,Ostermann, N.,Randl, S.,Yoon, T.,Mac Sweeney, A.,Cumin, F.,Lorthiois, E.,Rudisser, S.,Erbel, P.,Maibaum, J.
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D.
ACS Med Chem Lett, 9:490-495, 2018
Cited by
PubMed: 29795765
DOI: 10.1021/acsmedchemlett.8b00104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.67 Å)
Structure validation

217705

건을2024-03-27부터공개중

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