6FSO

Crystal Structure of TGT in complex with methyl({[5-(pyridin-3-yloxy)furan-2-yl]methyl})amine

6FSO の概要

• エントリーDOI: 10.2210/pdb6fso/pdb
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (9 entities in total)
• 機能のキーワード: tgt, trna, guanine exchange enzyme, protein interface, transferase
• 由来する生物種: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42833.05

構造登録者

Hassaan, E.,Heine, A.,Klebe, G. (登録日: 2018-02-20, 公開日: 2019-03-20, 最終更新日: 2024-01-17)

• 主引用文献: Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G.; Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies.; Chemmedchem, 15:324-337, 2020; PubMed: 31808981; DOI: 10.1002/cmdc.201900604

実験手法

X-RAY DIFFRACTION (1.449 Å)