6FS8

Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA)

6FS8 の概要

• エントリーDOI: 10.2210/pdb6fs8/pdb
• 分子名称: Polymerase acidic protein, Baloxavir acid, MANGANESE (II) ION, ... (4 entities in total)
• 機能のキーワード: influenza, endonuclease, inhibitor, viral protein
• 由来する生物種: Influenza B virus (B/Memphis/13/2003)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48224.03

構造登録者

Cusack, S.,Speranzini, V. (登録日: 2018-02-19, 公開日: 2018-07-11, 最終更新日: 2024-01-17)

• 主引用文献: Omoto, S.,Speranzini, V.,Hashimoto, T.,Noshi, T.,Yamaguchi, H.,Kawai, M.,Kawaguchi, K.,Uehara, T.,Shishido, T.,Naito, A.,Cusack, S.; Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.; Sci Rep, 8:9633-9633, 2018; PubMed: 29941893; DOI: 10.1038/s41598-018-27890-4

実験手法

X-RAY DIFFRACTION (1.8 Å)