6FRX

PKA variant as Aurora B mimic in complex with a dianilinopyrimidine inhibitor

6FRX の概要

• エントリーDOI: 10.2210/pdb6frx/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ~{N}-[3-[(5-chloranyl-2-phenylazanyl-pyrimidin-4-yl)amino]phenyl]prop-2-enamide, ... (4 entities in total)
• 機能のキーワード: protein kinase, surrogate model, catalytic domain, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43448.69

構造登録者

Engh, R.A.,Kazi, A.A. (登録日: 2018-02-16, 公開日: 2019-03-13)

• 主引用文献: Engh, R.A.,Kazi, A.A.; PKA variant as Aurora B mimic in complex with a dianilinopyrimidine inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (1.88 Å)