6FKP
Crystal structure of BAZ2A PHD zinc finger in complex with H3 10-mer AA mutant peptide
Summary for 6FKP
Entry DOI | 10.2210/pdb6fkp/pdb |
Descriptor | Bromodomain adjacent to zinc finger domain protein 2A, ALA-ARG-THR-ALA-ALA-THR-ALA-ARG, ZINC ION, ... (6 entities in total) |
Functional Keywords | transcription, phd zinc finger, bromodomain, baz2a, histone, epigenetic, h3 |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus, nucleolus : Q9UIF9 |
Total number of polymer chains | 7 |
Total formula weight | 30396.59 |
Authors | Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (deposition date: 2018-01-24, release date: 2018-03-21, Last modification date: 2024-05-08) |
Primary citation | Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach. ACS Chem. Biol., 13:915-921, 2018 Cited by PubMed: 29529862DOI: 10.1021/acschembio.7b01093 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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