6FKP

Crystal structure of BAZ2A PHD zinc finger in complex with H3 10-mer AA mutant peptide

Summary for 6FKP

• Entry DOI: 10.2210/pdb6fkp/pdb
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, ALA-ARG-THR-ALA-ALA-THR-ALA-ARG, ZINC ION, ... (6 entities in total)
• Functional Keywords: transcription, phd zinc finger, bromodomain, baz2a, histone, epigenetic, h3
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus, nucleolus : Q9UIF9
• Total number of polymer chains: 7
• Total formula weight: 30396.59

Authors

Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (deposition date: 2018-01-24, release date: 2018-03-21, Last modification date: 2024-05-08)

• Primary citation: Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A.; Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.; ACS Chem. Biol., 13:915-921, 2018; PubMed: 29529862; DOI: 10.1021/acschembio.7b01093

Experimental method

X-RAY DIFFRACTION (2 Å)