6FI0

Crystal structure of BAZ2A PHD zinc finger in complex with Fr 19

Summary for 6FI0

Entry DOI	10.2210/pdb6fi0/pdb
Descriptor	Bromodomain adjacent to zinc finger domain protein 2A, ZINC ION, PHOSPHATE ION, ... (7 entities in total)
Functional Keywords	transcription, phd zinc finger, bromodomain, baz2a, fragment, fr 19, fr19, epigenetic, ligandability
Biological source	Homo sapiens (Human)
Cellular location	Nucleus, nucleolus : Q9UIF9
Total number of polymer chains	4
Total formula weight	27856.76
Authors	Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (deposition date: 2018-01-16, release date: 2018-03-21, Last modification date: 2024-01-17)
Primary citation	Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach. ACS Chem. Biol., 13:915-921, 2018 Cited by PubMed: 29529862 DOI: 10.1021/acschembio.7b01093 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation