6FI0

Crystal structure of BAZ2A PHD zinc finger in complex with Fr 19

6FI0 の概要

• エントリーDOI: 10.2210/pdb6fi0/pdb
• 分子名称: Bromodomain adjacent to zinc finger domain protein 2A, ZINC ION, PHOSPHATE ION, ... (7 entities in total)
• 機能のキーワード: transcription, phd zinc finger, bromodomain, baz2a, fragment, fr 19, fr19, epigenetic, ligandability
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus, nucleolus : Q9UIF9
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 27856.76

構造登録者

Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (登録日: 2018-01-16, 公開日: 2018-03-21, 最終更新日: 2024-01-17)

• 主引用文献: Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A.; Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.; ACS Chem. Biol., 13:915-921, 2018; PubMed: 29529862; DOI: 10.1021/acschembio.7b01093

実験手法

X-RAY DIFFRACTION (1.9 Å)