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6FGC

Crystal structure of Gephyrin E domain in complex with Artesunate

Summary for 6FGC
Entry DOI10.2210/pdb6fgc/pdb
DescriptorGephyrin, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (10 entities in total)
Functional Keywordsantimalarial compound, artemisinins and its derivatives, inhibitory neurotransmission, moco biosynthesis, structural protein
Biological sourceRattus norvegicus (Rat)
Total number of polymer chains1
Total formula weight47461.31
Authors
Kasaragod, V.B.,Schindelin, H. (deposition date: 2018-01-10, release date: 2019-01-16, Last modification date: 2024-01-17)
Primary citationKasaragod, V.B.,Hausrat, T.J.,Schaefer, N.,Kuhn, M.,Christensen, N.R.,Tessmer, I.,Maric, H.M.,Madsen, K.L.,Sotriffer, C.,Villmann, C.,Kneussel, M.,Schindelin, H.
Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Neuron, 101:673-689.e11, 2019
Cited by
PubMed: 30704910
DOI: 10.1016/j.neuron.2019.01.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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