6FGC

Crystal structure of Gephyrin E domain in complex with Artesunate

6FGC の概要

• エントリーDOI: 10.2210/pdb6fgc/pdb
• 分子名称: Gephyrin, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (10 entities in total)
• 機能のキーワード: antimalarial compound, artemisinins and its derivatives, inhibitory neurotransmission, moco biosynthesis, structural protein
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47461.31

構造登録者

Kasaragod, V.B.,Schindelin, H. (登録日: 2018-01-10, 公開日: 2019-01-16, 最終更新日: 2024-01-17)

• 主引用文献: Kasaragod, V.B.,Hausrat, T.J.,Schaefer, N.,Kuhn, M.,Christensen, N.R.,Tessmer, I.,Maric, H.M.,Madsen, K.L.,Sotriffer, C.,Villmann, C.,Kneussel, M.,Schindelin, H.; Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.; Neuron, 101:673-689.e11, 2019; PubMed: 30704910; DOI: 10.1016/j.neuron.2019.01.001

実験手法

X-RAY DIFFRACTION (1.5 Å)