6FG0

Crystal structure of R. ruber ADH-A, mutant Y54G, F43T, L119Y, F282W

6FG0 の概要

• エントリーDOI: 10.2210/pdb6fg0/pdb
• 分子名称: Alcohol dehydrogenase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: alcohol dehydrogenase mutant variant, nadh-dependent, zn2+-dependent, rossmann fold, oxidoreductase
• 由来する生物種: Rhodococcus sp. M8
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 147324.52

構造登録者

Dobritzsch, D.,Maurer, D.,Hamnevik, E.,Enugala, T.R.,Widersten, M. (登録日: 2018-01-09, 公開日: 2018-12-19, 最終更新日: 2024-01-17)

• 主引用文献: Maurer, D.,Enugala, T.R.,Hamnevik, E.,Bauer, P.,Luking, M.,Hillier, H.,Kamerlin, S.C.L.,Dobritzsch, D.,Widersten, M.; Stereo- and Regioselectivity in Catalyzed Transformation of a 1,2-Disubstituted Vicinal Diol and the Corresponding Diketone by Wild Type and Laboratory Evolved Alcohol Dehydrogenases; Acs Catalysis, 8:7526-7538, 2018; DOI: 10.1021/acscatal.8b01762

実験手法

X-RAY DIFFRACTION (1.74 Å)