6FFD

Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone

6FFD の概要

• エントリーDOI: 10.2210/pdb6ffd/pdb
• 分子名称: Bromodomain-containing protein 4, 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone (3 entities in total)
• 機能のキーワード: inhibitor, histone, epigenetic reader, bromodomain, brd4, bromodomain containing protein 4, antagonist, transcription
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13917.08

構造登録者

Chung, C. (登録日: 2018-01-06, 公開日: 2019-01-30, 最終更新日: 2024-05-08)

• 主引用文献: Chung, C.; Design and Synthesis of Tetrahydroquinoxalines as Domain Selective BET Inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.83 Å)