6FD2

Radical SAM 1,2-diol dehydratase AprD4 in complex with its substrate paromamine

6FD2 の概要

• エントリーDOI: 10.2210/pdb6fd2/pdb
• 分子名称: Putative apramycin biosynthetic oxidoreductase 4, paromamine, IRON/SULFUR CLUSTER, ... (6 entities in total)
• 機能のキーワード: radical sam, fes-cluster containing enzyme, 1, 2-diol dehydratase, biosynthetic protein
• 由来する生物種: Streptoalloteichus tenebrarius (strain ATCC 17920 / DSM 40477 / NCIB 11028) (Streptomyces tenebrarius)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102915.54

構造登録者

Liu, W.Q.,Amara, P.,Mouesca, J.M.,Ji, X.,Renoux, O.,Martin, L.,Zhang, C.,Zhang, Q.,Nicolet, Y. (登録日: 2017-12-21, 公開日: 2018-01-17, 最終更新日: 2024-01-17)

• 主引用文献: Liu, W.Q.,Amara, P.,Mouesca, J.M.,Ji, X.,Renoux, O.,Martin, L.,Zhang, C.,Zhang, Q.,Nicolet, Y.; 1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.; J. Am. Chem. Soc., 140:1365-1371, 2018; PubMed: 29300094; DOI: 10.1021/jacs.7b10501

実験手法

X-RAY DIFFRACTION (2.55 Å)