6F6S

CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH benztropine

Summary for 6F6S

Entry DOI	10.2210/pdb6f6s/pdb
Related	6F5U 6F6I 6F6N
Descriptor	Envelope glycoprotein,Envelope glycoprotein,GP1, Envelope glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	ebola virus, filoviridae, envelope glycoprotein, protein inhibitor complex, ibuprofen, benztropine, bepridil, paroxetine, sertraline, toremifene, viral protein
Biological source	Zaire ebolavirus (strain Mayinga-76) (ZEBOV) More
Total number of polymer chains	2
Total formula weight	58337.03
Authors	Ren, J.,Zhao, Y.,Fry, E.E.,Stuart, D.I. (deposition date: 2017-12-06, release date: 2018-01-03, Last modification date: 2024-01-17)
Primary citation	Ren, J.,Zhao, Y.,Fry, E.E.,Stuart, D.I. Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection. J. Med. Chem., 61:724-733, 2018 Cited by PubMed: 29272110 DOI: 10.1021/acs.jmedchem.7b01249 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation