Crystal structure of tetrameric human Rabin8 GEF domain

Replaces:  5OAG

Summary for 6F6P

DescriptorRab-3A-interacting protein (3 entities in total)
Functional Keywordsrabin8, gef, guanine nucleotide exchange factor, tetramer, rab3i, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm Q96QF0 Q96QF0
Total number of polymer chains4
Total molecular weight47994.94
Lorentzen, E.,Vetter, M. (deposition date: 2017-12-06, release date: 2017-12-13, Last modification date: 2018-03-14)
Primary citation
Vetter, M.,Boegholm, N.,Christensen, A.,Bhogaraju, S.,Andersen, M.B.,Lorentzen, A.,Lorentzen, E.
Crystal structure of tetrameric human Rabin8 GEF domain.
Proteins, 86:405-413, 2018
PubMed: 29318657 (PDB entries with the same primary citation)
DOI: 10.1002/prot.25455
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.305300.3%6.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution