6F6I

CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH PAROXETINE

6F6I の概要

• エントリーDOI: 10.2210/pdb6f6i/pdb
• 関連するPDBエントリー: 6F5U
• 分子名称: Envelope glycoprotein,GP,GP1, Envelope glycoprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: ebola virus, filoviridae, envelope glycoprotein, protein inhibitor complex, ibuprofen, benztropine, bepridil, paroxetine, sertraline, toremifene, viral protein
• 由来する生物種: Ebola virus; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57726.52

構造登録者

Ren, J.,Zhao, Y.,Fry, E.E.,Stuart, D.I. (登録日: 2017-12-05, 公開日: 2018-01-03, 最終更新日: 2024-01-17)

• 主引用文献: Ren, J.,Zhao, Y.,Fry, E.E.,Stuart, D.I.; Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.; J. Med. Chem., 61:724-733, 2018; PubMed: 29272110; DOI: 10.1021/acs.jmedchem.7b01249

実験手法

X-RAY DIFFRACTION (2.4 Å)