6F5T

Crystal Structure of KDM4D with tetrazole ligand GF057

Summary for 6F5T

• Entry DOI: 10.2210/pdb6f5t/pdb
• Descriptor: Lysine-specific demethylase 4D, ZINC ION, SULFATE ION, ... (8 entities in total)
• Functional Keywords: kdm4d, ligand binding, ligand optimization, drug development, tetrazole, inhibitor design, cancer, epigenetics, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 39470.49

Authors

Malecki, P.H.,Link, A.,Weiss, M.S.,Heinemann, U. (deposition date: 2017-12-02, release date: 2018-12-12, Last modification date: 2024-01-17)

• Primary citation: Malecki, P.H.,Link, A.,Weiss, M.S.,Heinemann, U.; Crystal Structure of KDM4D with tetrazole ligand; To be published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)