6F4L

Structure of quinolinate synthase with inhibitor-derived quinolinate

Summary for 6F4L

Entry DOI	10.2210/pdb6f4l/pdb
Descriptor	Quinolinate synthase A, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... (6 entities in total)
Functional Keywords	nad biosynthesis, iron sulfur cluster, transferase
Biological source	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Cellular location	Cytoplasm : Q9X1X7
Total number of polymer chains	1
Total formula weight	35418.10
Authors	Volbeda, A.,Fontecilla-Camps, J.C. (deposition date: 2017-11-29, release date: 2018-04-25, Last modification date: 2024-01-17)
Primary citation	Volbeda, A.,Saez Cabodevilla, J.,Darnault, C.,Gigarel, O.,Han, T.H.,Renoux, O.,Hamelin, O.,Ollagnier-de-Choudens, S.,Amara, P.,Fontecilla-Camps, J.C. Crystallographic Trapping of Reaction Intermediates in Quinolinic Acid Synthesis by NadA. ACS Chem. Biol., 13:1209-1217, 2018 Cited by PubMed: 29641168 DOI: 10.1021/acschembio.7b01104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation