6F4L
Structure of quinolinate synthase with inhibitor-derived quinolinate
Summary for 6F4L
Entry DOI | 10.2210/pdb6f4l/pdb |
Descriptor | Quinolinate synthase A, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... (6 entities in total) |
Functional Keywords | nad biosynthesis, iron sulfur cluster, transferase |
Biological source | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) |
Cellular location | Cytoplasm : Q9X1X7 |
Total number of polymer chains | 1 |
Total formula weight | 35418.10 |
Authors | Volbeda, A.,Fontecilla-Camps, J.C. (deposition date: 2017-11-29, release date: 2018-04-25, Last modification date: 2024-01-17) |
Primary citation | Volbeda, A.,Saez Cabodevilla, J.,Darnault, C.,Gigarel, O.,Han, T.H.,Renoux, O.,Hamelin, O.,Ollagnier-de-Choudens, S.,Amara, P.,Fontecilla-Camps, J.C. Crystallographic Trapping of Reaction Intermediates in Quinolinic Acid Synthesis by NadA. ACS Chem. Biol., 13:1209-1217, 2018 Cited by PubMed: 29641168DOI: 10.1021/acschembio.7b01104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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