6F1C

C1rC1s complex

Summary for 6F1C

• Entry DOI: 10.2210/pdb6f1c/pdb
• Descriptor: Complement C1r subcomponent, Complement C1s subcomponent, beta-D-galactopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: cub domain, egf-like domain, complement, c1r-c1s, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 132949.33

Authors

Almitairi, J.O.M.,Venkatraman Girija, U.,Furze, C.M.,Simpson-Gray, X.,Badakshi, F.,Marshall, J.E.,Mitchell, D.A.,Moody, P.C.E.,Wallis, R. (deposition date: 2017-11-21, release date: 2018-01-17, Last modification date: 2024-01-17)

• Primary citation: Almitairi, J.O.M.,Venkatraman Girija, U.,Furze, C.M.,Simpson-Gray, X.,Badakshi, F.,Marshall, J.E.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.E.,Wallis, R.; Structure of the C1r-C1s interaction of the C1 complex of complement activation.; Proc. Natl. Acad. Sci. U.S.A., 115:768-773, 2018; PubMed: 29311313; DOI: 10.1073/pnas.1718709115

Experimental method

X-RAY DIFFRACTION (4.2 Å)