6EZW

Crystal structure of a llama VHH antibody BCD090-M2 against human ErbB3 in space group C2

6EZW の概要

• エントリーDOI: 10.2210/pdb6ezw/pdb
• 分子名称: VHH antibody BCD090-M2 (2 entities in total)
• 機能のキーワード: vhh, llama antibody, single-domain antibody, nanobody, erbb3, her3, receptor tyrosine kinase, immune system
• 由来する生物種: Lama glama (Llama)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13967.40

構造登録者

Eliseev, I.E.,Yudenko, A.N.,Vysochinskaya, V.V.,Svirina, A.A.,Evstratyeva, A.V.,Drozhzhachih, M.S.,Krendeleva, E.A.,Vladimirova, A.K.,Nemankin, T.A.,Ekimova, V.M.,Ulitin, A.B.,Lomovskaya, M.I.,Yakovlev, P.A.,Moiseenko, F.V.,Chakchir, O.B. (登録日: 2017-11-16, 公開日: 2017-11-29, 最終更新日: 2024-01-17)

• 主引用文献: Eliseev, I.E.,Yudenko, A.N.,Vysochinskaya, V.V.,Svirina, A.A.,Evstratyeva, A.V.,Drozhzhachih, M.S.,Krendeleva, E.A.,Vladimirova, A.K.,Nemankin, T.A.,Ekimova, V.M.,Ulitin, A.B.,Lomovskaya, M.I.,Yakovlev, P.A.,Bukatin, A.S.,Knyazev, N.A.,Moiseenko, F.V.,Chakchir, O.B.; Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor.; F1000Res, 7:57-57, 2018; PubMed: 30430004; DOI: 10.12688/f1000research.13612.1

実験手法

X-RAY DIFFRACTION (1.59842847381 Å)