6EZN

Cryo-EM structure of the yeast oligosaccharyltransferase (OST) complex

6EZN の概要

• エントリーDOI: 10.2210/pdb6ezn/pdb
• 関連するPDBエントリー: 6EZN
• EMDBエントリー: 4161 4257
• 分子名称: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• 機能のキーワード: ost complex, oligosaccharyltransferase, n-linked glycosylation, yeast, membrane protein
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 291410.84

構造登録者

Wild, R.,Kowal, J.,Eyring, J.,Ngwa, E.M.,Aebi, M.,Locher, K.P. (登録日: 2017-11-16, 公開日: 2018-01-17, 最終更新日: 2022-12-07)

• 主引用文献: Ramirez, A.S.,de Capitani, M.,Pesciullesi, G.,Kowal, J.,Bloch, J.S.,Irobalieva, R.N.,Reymond, J.L.,Aebi, M.,Locher, K.P.; Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.; Nat Commun, 13:7296-7296, 2022; PubMed: 36435935; DOI: 10.1038/s41467-022-35067-x

実験手法

ELECTRON MICROSCOPY (3.3 Å)