6EZJ
Imidazoleglycerol-phosphate dehydratase
Summary for 6EZJ
| Entry DOI | 10.2210/pdb6ezj/pdb |
| EMDB information | 3999 |
| Descriptor | Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid (3 entities in total) |
| Functional Keywords | inhibitor, histidine biosynthesis, lyase, complex |
| Biological source | Arabidopsis thaliana (Thale cress) |
| Total number of polymer chains | 24 |
| Total formula weight | 544995.05 |
| Authors | Rawson, S.,Bisson, C.,Hurdiss, D.L.,Muench, S.P. (deposition date: 2017-11-15, release date: 2018-02-07, Last modification date: 2019-12-11) |
| Primary citation | Rawson, S.,Bisson, C.,Hurdiss, D.L.,Fazal, A.,McPhillie, M.J.,Sedelnikova, S.E.,Baker, P.J.,Rice, D.W.,Muench, S.P. Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115:1795-1800, 2018 Cited by PubMed: 29434040DOI: 10.1073/pnas.1708839115 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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